DNA Microarray Gene Expression Heatmap

A gene expression heatmap figure in the style of a Genome Biology or Molecular Cell paper supplementary figure. The main panel is a 20 × 12 grid of square cells representing 20 genes (rows, labelled with fictional gene symbols on the y-axis: GFAB1, PROX2, NCDM3, SYKL4, RHTP5, etc.) across 12 experimental conditions (columns, labelled on the x-axis: "Ctrl-1", "Ctrl-2", "Ctrl-3", "Treat-A-1" through "Treat-A-3", "Treat-B-1" through "Treat-B-3", "Treat-C-1" through "Treat-C-3"). Cell colour encodes expression level using a diverging palette: deep navy blue for strong downregulation (log₂FC = −3), white for no change (0), and deep crimson for strong upregulation (+3). A vertical colour bar legend on the right is labelled "log₂ Fold Change" with a continuous gradient from navy to white to crimson and tick marks at −3, −1.5, 0, +1.5, +3. A dendrogram on the left y-axis (thin black branching lines) clusters the genes by expression profile similarity. A horizontal dendrogram on the top x-axis clusters conditions. Three coloured column-group brackets above the top dendrogram label "Control" (grey), "Treatment A" (teal), "Treatment B" (coral), "Treatment C" (gold). Black thin grid lines between cells at 0.5 pt. All axis labels in 8 pt, title label "Differentially Expressed Genes (n=20)" in 10 pt bold at the top. White background.

一张基因组学期刊附图风格的基因表达热图，主面板为 20×12 格子：20 个基因（行，y 轴标虚构基因符号 GFAB1、PROX2、NCDM3 等）×12 实验条件（列，x 轴标 "Ctrl-1/2/3"、"Treat-A-1/2/3"、"Treat-B-1/2/3"、"Treat-C-1/2/3"）。颜色编码 log₂FC：深海军蓝（−3 下调）、白色（0）、深深红（+3 上调）。右侧竖向颜色条图例 「Ctrl-1」，刻度 −3/−1.5/0/+1.5/+3。左侧基因聚类树状图，顶部条件聚类树状图，顶部三色括号分组 「Ctrl-2」（灰）、「Ctrl-3」（青绿）、「Treat-A-1」（珊瑚）、「Differentially Expressed Genes (n=20)」（金色）。0.5pt 细黑格线，8pt 轴标，顶部 10pt 粗体标题 "Differentially Expressed Genes (n=20)"，白色背景。